Endocrine Abstracts

Introduction: Congenital idiopathic hypogonadotropic hypogonadism is a rare genetic disorder caused by an isolated defect in GnRH secretion by the hypothalamus or, less frequently, by a defect in the action of GnRH on pituitary gonadotropes. The majority of cases are sporadic but there are also family forms. We report a case of one family.Case report: These are 2 brothers with a family history of primary infertility in the maternal uncle. An 18-year-old ...

Introduction: Detection of TSH-receptor autoantibodies in the diagnosis of graves disease is well established. however these autoantibodies may not be always present in some forms of correctly observed autoimmune hyperthyroidism. Here, we describe a patient with hyperthyroid Graves’ disease without detectable thyrotropin receptor antibodies.Case report: She was A 55-year-old woman, presented with a 2 years history of increased sweating, palpitations...

Introducion: Pituitary apoplexy is an endocrine emergency that is a rare complication of pituitary adenomas and exceptional in ACTH adenomas. We report a case of apoplexy on corticotropic adenoma with intermittent secretion.Case report: The patient was 41 years old woman, she presented in 2012 a period of symptomatic hypercortisolism. Urinary free cortisol was elevated to 113 μg/24H, Low-dose dexamethasone testing was negative, ACTH was elevated to ...

Introduction: Untreated hypothyroidism may lead to decompensation of a patient’s homeostasis. While the association between hypothyroidism and anemia has been noted previously, there are very few, cases of white cell lines and platelet counts being affected by hypothyroidism alone. To demonstrate a rare but significant manifestation of hypothyroidism, we present a unique and interesting case of pancytopenia secondary to severe hypothyroidismCase rep...

Introduction: Untreated hypothyroidism may lead to decompensation of a patient’s homeostasis. While the association between hypothyroidism and anemia has been noted previously, there are very few, cases of white cell lines and platelet counts being affected by hypothyroidism alone. To demonstrate a rare but significant manifestation of hypothyroidism, we present a unique and interesting case of pancytopenia secondary to severe hypothyroidism.Case re...

Introduction: Hypoglycaemia in non diabetic patients is a decrease of blood glucose below a threshold of 0.5 g/l, corresponds to a pathological situation, with many etiologies and whose management constitutes a real challenge, both symptomatic and etiological. The purpose of this study is to highlight the profile of these hypoglycaemia and their management.Patients and method: We have collected cases of hypoglycaemia in non-diabetic subjects encountered ...

Definition: Fake hypoglycaemia in children and adults is due to self-administration of insulin or insulin secretagogue. They represent one of the best described facets of the Münchhausen syndrome. Here we report four cases of false hypoglycemia following insulin injection.Material and method: Prospective study that took place over 2 years to collect 4 hospitalized cases for etiological assessment of severe hypoglycaemia up to 0.2 g/l and complicated...

Introduction: When hypoglycemia is deep and repeated, it can induce various neurological disorders, including epileptic seizures. The link between hypoglycemia and epileptic phenomena is complex and poorly explained. We report 3 cases of epilepsy induced by repeated episodes of deep hypoglycemia.Cases report: Mr D.M, 48 years old, with a history of 3 episodes of hypoglycemic coma, admitted for status epilepticus with a blood glucose level of 0.4 g /l; ce...

Introduction: Central diabetes insipidus (DIC) is defined by the excretion of large volume of diluted urine, secondary to an absolute or relative deficiency of endogenous vasopressin. We report three observations of children with central diabetes insipidus.Results: This study reports the case of three patients whose average age was thirteen years old (11, 13 and 15 y). The occurrence of polyuria-polydipsia syndrome was the main reason for consultation an...

Introduction: When hypoglycemia is deep and repeated, it can induce various neurological disorders, including epileptic seizures. The link between hypoglycemia and epileptic phenomena is complex and poorly explained. We report 3 cases of epilepsy induced by repeated episodes of deep hypoglycemia.Cases report: Mr D.M, 48 years old, with a history of 3 episodes of hypoglycemic coma, admitted for status epilepticus with a blood glucose level of 0.4 g/l; cer...